Will multiple monitors or much bigger monitor affect computer performance? [duplicate]

I have two questions about the monitor's impact on the computer's performance:

1. Will multiple monitors affect computer performance?
2. will a bigger monitor (43") slow down the computer's performance compared with a smaller monitor (22")?

When we compare, we assume all monitors are full in live stock charts, these charts will be updated every second or shorter. Do you think more monitors or much bigger monitors will make the computer's response time longer? Is there a way to test this?